Dactolisib (BEZ235)

Dactolisib (BEZ235, NVP-BEZ235) is a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM in cell-free assays, respectively. Inhibits ATR with IC50 of 21 nM in 3T3TopBP1-ER cell. Dactolisib induces autophagy and suppresses HIV-1 replication. Phase 2.

Price Not Available 50mg Dactolisib (BEZ235) Supplier Page

Trivial name	NVP-BEZ235
Catalog Number	S1009
Molecular Formula	C8H14O2
CAS#	915019-65-7
Inchi	InChI=1S/C8H14O2/c9-8(10)6-7-4-2-1-3-5-7/h7H,1-6H2,(H,9,10)
Inchi Key	LJOODBDWMQKMFB-UHFFFAOYSA-N
SMILES	C1CCC(CC1)CC(=O)O
Size	50mg
Supplier Page	http://www.selleckchem.com/products/BEZ235.html
Additional Information	https://file.selleck.cn/downloads/struct/BEZ235-NVP-BEZ235-chemical-structure-S1009.gif