P529

A potent PI3K/Akt/mTOR inhibitor that inhibits the TORC1 and TORC2 complexes. Displays inhibition of both Akt signaling and mTOR signaling similarly in tumor and vasculature. P529 inhibits tumor growth, angiogenesis and vascular permeability.

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Catalog Number ABM-013
Alternative Name(s) 3-(4-methoxybenzyloxy)-8-(1-hydroxyethyl)-2-methoxy-6H-benzo[c]chromen-6-one ; Palomid 529
CAS# 914913-88-5
Inchi InChI=1S/C24H22O6/c1-14(25)16-6-9-18-19-11-22(28-3)23(12-21(19)30-24(26)20(18)10-16)29-13-15-4-7-17(27-2)8-5-15/h4-12,14,25H,13H2,1-3H3
Inchi Key YEAHTLOYHVWAKW-UHFFFAOYSA-N
SMILES CC(C1=CC2=C(C=C1)C3=CC(=C(C=C3OC2=O)OCC4=CC=C(C=C4)OC)OC)O
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Supplier Page https://www.agingclocks.com/p529-item-1458.html