Rolapitant hydrochloride hydrate

Rolapitant hydrochloride hydrate(SCH619734 hydrochloride hydrate) is a long-acting, extremely selective antagonist of the Nk-1 receptor antagonist (NK-1RA) with antiemetic activity. It significantly penetrates the central nervous system (CNS) and used clinically to prevent chemotherapy-induced nausea and vomiting (CINV) in cancer patients undergoing high and moderate emetogenic chemotherapy.

Price Not Available 1g Rolapitant hydrochloride hydrate Supplier Page

Trivial name	SCH619734 hydrochloride hydrate
Catalog Number	E4853
Molecular Formula	C21H27N7O3
CAS#	914462-92-3
Inchi	InChI=1S/C21H27N7O3/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,22,27)/t13-/m0/s1
Inchi Key	KGPGFQWBCSZGEL-ZDUSSCGKSA-N
SMILES	CCN1C2=C(C(=NC=C2OCC3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N
Size	1g
Supplier Page	http://www.selleckchem.com/products/rolapitant-hydrochloride-hydrate.html
Additional Information	https://file.selleck.cn/downloads/struct/E4853-Rolapitant-hydrochloride-hydrate-chemical-structure.png