AMG-458
AMG 458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.
| Trivial name | N/A |
| Catalog Number | S2747 |
| Molecular Formula | C11H8N2O3S2 |
| CAS# | 913376-83-7 |
| Inchi | InChI=1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1 |
| Inchi Key | BJGNCJDXODQBOB-SSDOTTSWSA-N |
| SMILES | C1C(N=C(S1)C2=NC3=C(S2)C=C(C=C3)O)C(=O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/amg458.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AMG-458-chemical-structure-s2747.gif |