Belumosudil (KD025)
Belumosudil (KD025, SLx-2119) is an orally available, and selective ROCK2 inhibitor with IC50 and Ki of 60 nM and 41 nM, respectively. Phase 2.
| Trivial name | SLx-2119 |
| Catalog Number | S7936 |
| Molecular Formula | C26H24N6O2 |
| CAS# | 911417-87-3 |
| Inchi | InChI=1S/C26H24N6O2/c1-16(2)28-24(33)15-34-20-7-5-6-17(13-20)25-30-23-9-4-3-8-21(23)26(31-25)29-19-10-11-22-18(12-19)14-27-32-22/h3-14,16H,15H2,1-2H3,(H,27,32)(H,28,33)(H,29,30,31) |
| Inchi Key | GKHIVNAUVKXIIY-UHFFFAOYSA-N |
| SMILES | CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC3=CC=CC=C3C(=N2)NC4=CC5=C(C=C4)NN=C5 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/kd025-(slx-2119).html |
| Additional Information | https://file.selleck.cn/downloads/struct/KD025-(SLx-2119)-chemical-structure-s7936.gif |