Domatinostat (4SC-202)
Domatinostat (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1.
| Catalog Number | S7555 |
| Molecular Formula | C23H21N5O3S |
| CAS# | 910462-43-0 |
| Inchi | InChI=1S/C23H21N5O3S/c1-27-16-19(14-25-27)18-7-9-20(10-8-18)32(30,31)28-13-12-17(15-28)6-11-23(29)26-22-5-3-2-4-21(22)24/h2-16H,24H2,1H3,(H,26,29)/b11-6+ |
| Inchi Key | PRXXYMVLYKJITB-IZZDOVSWSA-N |
| SMILES | CN1C=C(C=N1)C2=CC=C(C=C2)S(=O)(=O)N3C=CC(=C3)C=CC(=O)NC4=CC=CC=C4N |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/4sc-202.html |
| Additional Information | https://file.selleck.cn/downloads/struct/4sc-202-chemical-structure-s7555.gif |