A-83-01
A-83-01 is a potent inhibitor of TGF-β type I receptor (ALK5-TD) with IC50 of 12 nM. A-83-01 also inhibits the transcription induced by activin/nodal type I receptor (ALK4-TD) and nodal type I receptor (ALK7-TD) with IC50 of 45 nM and 7.5 nM, respectively.Solutions are unstable and should be fresh-prepared.
| Trivial name | N/A |
| Catalog Number | S7692 |
| Molecular Formula | C25H19N5S |
| CAS# | 909910-43-6 |
| SMILES | CC1=NC(=CC=C1)C2=NN(C=C2C3=CC=NC4=CC=CC=C34)C(=S)NC5=CC=CC=C5 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/a-83-01.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s7692-a-83-01-chemical-structure.gif |