Diminazene Aceturate
Diminazene(Diminazene diaceturate) is a di-amidine also known as 4,4-(1-Triazene–1,3–diyl)bis(benzenecarboximidamide), used as an effective trypanocidal agent. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties.
| Trivial name | Diminazene diaceturate |
| Catalog Number | S4104 |
| Molecular Formula | C14H15N7.2C4H7NO3 |
| CAS# | 908-54-3 |
| Inchi | InChI=1S/C14H15N7.2C4H7NO3/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18;2*1-3(6)5-2-4(7)8/h1-8H,(H3,15,16)(H3,17,18)(H,19,20);2*2H2,1H3,(H,5,6)(H,7,8) |
| Inchi Key | OKQSSSVVBOUMNZ-UHFFFAOYSA-N |
| SMILES | CC(=O)NCC(=O)O.CC(=O)NCC(=O)O.C1=CC(=CC=C1C(=N)N)NN=NC2=CC=C(C=C2)C(=N)N |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/diminazene-aceturate.html |
| Additional Information | https://file.selleck.cn/downloads/struct/diminazene-aceturate-chemical-structure-S4104.gif |