Locostatin | MedChemExpress (MCE)
Locostatin (UIC-1005) is a potent RKIP inhibitor. Locostatin binds Raf kinase inhibitor RKIP protein and disrupts the interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2. Locostatin inhibits cell proliferation and migration. Locostatin can be used to synthesize chemical probes toward PEBP-proteins. Locostatin aggravates thioacetamide (HY-Y0698)-induced acute liver failure in mice [1][2][3].
Trivial name | Locostatin |
Catalog Number | HY-W013411A |
Alternative Name(s) | UIC-1005 |
Research Area | Cancer |
CAS# | 90719-30-5 |
Purity | 99.82% |
SMILES | O=C1OC[C@H](CC2=CC=CC=C2)N1C(/C=C/C)=O |
PubChem Chemical Structure ID | 5702600 |
Size | 50 mg |
Supplier Page | https://www.medchemexpress.com/locostatin.html |