AZ 960
AZ 960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki of <3 nM and 0.45 nM, 3-fold selectivity of AZ960 for JAK2 over JAK3. AZ 960 induces apoptosis and growth arrest.
| Trivial name | N/A |
| Catalog Number | S2214 |
| Molecular Formula | C21H21ClF3N7O3S |
| CAS# | 905586-69-8 |
| Inchi | InChI=1S/C21H20F3N7O3S.ClH/c1-31(35(2,33)34)19-12(4-3-7-25-19)10-26-18-15(21(22,23)24)11-27-20(30-18)28-14-5-6-16-13(8-14)9-17(32)29-16;/h3-8,11H,9-10H2,1-2H3,(H,29,32)(H2,26,27,28,30);1H |
| Inchi Key | RQEBZJWSAAWCAV-UHFFFAOYSA-N |
| SMILES | CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C.Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/AZ-960.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AZ-960-chemical-structure-S2214.gif |