AZ 960
AZ 960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki of <3 nM and 0.45 nM, 3-fold selectivity of AZ960 for JAK2 over JAK3. AZ 960 induces apoptosis and growth arrest.
| Trivial name | N/A |
| Catalog Number | S2214 |
| Molecular Formula | C23H21Cl2FN4O3 |
| CAS# | 905586-69-8 |
| Inchi | InChI=1S/C23H21Cl2FN4O3/c1-3-20(31)30-8-6-13(7-9-30)33-19-10-14-17(11-18(19)32-2)27-12-28-23(14)29-16-5-4-15(24)21(25)22(16)26/h3-5,10-13H,1,6-9H2,2H3,(H,27,28,29) |
| Inchi Key | LPFWVDIFUFFKJU-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=C(C=C3)Cl)Cl)F)OC4CCN(CC4)C(=O)C=C |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/AZ-960.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AZ-960-chemical-structure-S2214.gif |