AZ 960
AZ 960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki of <3 nM and 0.45 nM, 3-fold selectivity of AZ960 for JAK2 over JAK3. AZ 960 induces apoptosis and growth arrest.
| Trivial name | N/A |
| Catalog Number | S2214 |
| Molecular Formula | C18H16F2N6 |
| CAS# | 905586-69-8 |
| Inchi | InChI=1S/C18H16F2N6/c1-10-7-16(26-25-10)23-18-15(20)8-13(9-21)17(24-18)22-11(2)12-3-5-14(19)6-4-12/h3-8,11H,1-2H3,(H3,22,23,24,25,26)/t11-/m0/s1 |
| Inchi Key | SUNXHXDJOIXABJ-NSHDSACASA-N |
| SMILES | CC1=CC(=NN1)NC2=C(C=C(C(=N2)NC(C)C3=CC=C(C=C3)F)C#N)F |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/AZ-960.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AZ-960-chemical-structure-S2214.gif |