GDC-0879
GDC-0879 (AR-00341677) is a novel, potent, and selective B-Raf inhibitor with IC50 of 0.13 nM in A375 and Colo205 cells with activity against c-Raf as well; no inhibition known to other protein kinases.
| Trivial name | AR-00341677 |
| Catalog Number | S1104 |
| Molecular Formula | C19H18N4O2 |
| CAS# | 905281-76-7 |
| Inchi | InChI=1S/C19H18N4O2/c24-10-9-23-12-17(19(21-23)13-5-7-20-8-6-13)15-1-3-16-14(11-15)2-4-18(16)22-25/h1,3,5-8,11-12,24-25H,2,4,9-10H2/b22-18+ |
| Inchi Key | DEZZLWQELQORIU-RELWKKBWSA-N |
| SMILES | C1CC(=NO)C2=C1C=C(C=C2)C3=CN(N=C3C4=CC=NC=C4)CCO |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/GDC-0879.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GDC-0879-chemical-structure-S1104.gif |