PTK7/β-catenin-IN-2 | MedChemExpress (MCE)
PTK7/β-catenin-IN-2 (compound 04967) is an inhibitor of PTK7/β-catenin. It inhibits the binding of PTK7 to β-catenin (IC50: 5.6 μM), thereby inhibiting the signaling of the Wnt/β-catenin pathway. PTK7/β-catenin-IN-2 targets cell growth dependent on the Wnt signaling pathway and has anticancer properties. PTK7/β-catenin-IN-2 also showed inhibitory potency against p53 and MDM2 binding with an IC50 of 157.1 μM[1].
| Trivial name | PTK7/β-catenin-IN-2 |
| Catalog Number | HY-160489 |
| Research Area | Cancer |
| CAS# | 902434-29-1 |
| Purity | ≥98.0% |
| SMILES | O=C(CCC1=C(C)N2N=C(C3=CC=C(Cl)C=C3)C=C2N=C1C)NCCCN4CCN(CC4)C5=CC(Cl)=CC=C5 |
| Size | 10 mg |
| Supplier Page | https://www.medchemexpress.com/ptk7-β-catenin-in-2.html |