(R)-(-)-Gossypol
(R)-(-)-Gossypol (AT-101) is the levorotatory isomer of a natural product Gossypol. AT-101 is determined to bind to Bcl-2, Mcl-1 and Bcl-xL proteins with Kis of 260±30 nM, 170±10 nM, and 480±40 nM, respectively.
| Trivial name | AT-101, R-(-)-gossypol acetic acid |
| Catalog Number | E7791 |
| Molecular Formula | C16H17FIN3O4 |
| CAS# | 90141-22-3 |
| Inchi | InChI=1S/C16H17FIN3O4/c1-9-7-11(15(23)20-25-6-5-22)14(21(2)16(9)24)19-13-4-3-10(18)8-12(13)17/h3-4,7-8,19,22H,5-6H2,1-2H3,(H,20,23) |
| Inchi Key | RWEVIPRMPFNTLO-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(N(C1=O)C)NC2=C(C=C(C=C2)I)F)C(=O)NOCCO |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/r-gossypol.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7791-r-gossypol-chemical-structure-tube.png |