Fostamatinib (R788)

Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.

Price Not Available 5mg Fostamatinib (R788) Supplier Page
Trivial name N/A
Catalog Number S2625
Molecular Formula C23H26FN6O9P
CAS# 901119-35-5
Inchi InChI=1S/C23H26FN6O9P/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4/h6-10H,11H2,1-5H3,(H2,32,33,34)(H2,25,26,27,28,29)
Inchi Key GKDRMWXFWHEQQT-UHFFFAOYSA-N
SMILES CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)(O)O)C
Size 5mg
Supplier Page http://www.selleckchem.com/products/R7935788-Fostamatinib.html
Additional Information https://file.selleck.cn/downloads/struct/R788-chemical-structure-s2625.gif