Fostamatinib (R788)
Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.
Trivial name | N/A |
Catalog Number | S2625 |
Molecular Formula | C20H15NO3 |
CAS# | 901119-35-5 |
Inchi | InChI=1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24) |
Inchi Key | SLUINPGXGFUMLL-UHFFFAOYSA-N |
SMILES | C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/R7935788-Fostamatinib.html |
Additional Information | https://file.selleck.cn/downloads/struct/R788-chemical-structure-s2625.gif |