Fostamatinib (R788)
Fostamatinib (R788), a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.
Trivial name | N/A |
Catalog Number | S2625 |
Molecular Formula | C23H26FN6O9P |
CAS# | 901119-35-5 |
Inchi | InChI=1S/C23H26FN6O9P/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4/h6-10H,11H2,1-5H3,(H2,32,33,34)(H2,25,26,27,28,29) |
Inchi Key | GKDRMWXFWHEQQT-UHFFFAOYSA-N |
SMILES | CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)(O)O)C |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/R7935788-Fostamatinib.html |
Additional Information | https://file.selleck.cn/downloads/struct/R788-chemical-structure-s2625.gif |