KRAS inhibitor-3 | MedChemExpress (MCE)
KRAS inhibitor-3 is an inhibitor of KRAS inhibitor. KRAS inhibitor-3 binds to WT and oncogenic KRAS mutants with high affinity (KD: 0.28 μM for KRAS WT, 0.63 μM for KRAS G12C, 0.37 μM for KRAS G12D, 0.74 μM for KRAS Q61H). KRAS inhibitor-3 also disrupts interaction of KRAS with Raf[1].
| Trivial name | KRAS inhibitor-3 |
| Catalog Number | HY-122914 |
| Research Area | Cancer |
| CAS# | 900897-56-5 |
| Purity | 99.65% |
| SMILES | OCCN1CCN(CC1)C2=CC(C3=CC=CC=C3)=NC4=C(C(C)=NN42)C5=CC=CC=C5 |
| PubChem Chemical Structure ID | 4903596 |
| Size | 5 mg |
| Supplier Page | https://www.medchemexpress.com/kras-inhibitor-3.html |