AS-252424
AS-252424 is a novel, potent PI3Kγ inhibitor with IC50 of 30 nM in a cell-free assay with 30-fold selectivity for PI3Kγ than PI3Kα, and low inhibitory activity towards PI3Kδ/β.
| Trivial name | N/A |
| Catalog Number | S2671 |
| Molecular Formula | C17H11ClN4O |
| CAS# | 900515-16-4 |
| Inchi | InChI=1S/C17H11ClN4O/c18-11-6-13-12-3-5-20-9-15(12)21-16(13)14(7-11)22-17(23)10-2-1-4-19-8-10/h1-9,21H,(H,22,23) |
| Inchi Key | JZRMBDHPALEPDM-UHFFFAOYSA-N |
| SMILES | C1=CC(=CN=C1)C(=O)NC2=CC(=CC3=C2NC4=C3C=CN=C4)Cl |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/as-252424.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AS-252424-chemical-structure-s2671.gif |