Poloxamer 402 L122 (PEG-PPG-PEG, 5000 Averag) is a synthetic triblock copolymer of poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) (PEO-PPO-PEO). Poloxamer 402 L122 forms thermoreversible gel, which remains fluid at room temperature but becomes more viscous gel at body temperature. Poloxamer 402 L122 is utilized in drug delivery, tissue regeneration and generation of micellar system^[1].