NOX-6-18(GPR132-B-160)
NOX-6-18 (GPR132-B-160) is a potent and selective antagonist of GPR132 with an IC50 of 17 nM. It regulates macrophage reprogramming within pancreatic islets, reduces weight gain, and improves glucose metabolism in mice on a high-fat diet.
Trivial name | GPR132-B-160 |
Catalog Number | E4773 |
Molecular Formula | C14H21N3O.2HCl |
CAS# | 898211-21-7 |
Inchi | InChI=1S/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11-,12-;;/m1../s1 |
Inchi Key | IDDDVXIUIXWAGJ-LJDSMOQUSA-N |
SMILES | CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/nox-6-18-gpr132-b-160.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4773-NOX-6-18-GPR132-B-160-chemical-structure.png |