SC144

SC144 is the first-in-class orally active small-molecule gp130 inhibitor that induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes.

Price Not Available 5mg SC144 Supplier Page
Trivial name N/A
Catalog Number S7124
Molecular Formula C₁₆H₁₁FN₆O
CAS# 895158-95-9
Inchi InChI=1S/C16H11FN6O/c17-10-3-4-13-11(8-10)20-15(14-2-1-7-23(13)14)21-22-16(24)12-9-18-5-6-19-12/h1-9H,(H,20,21)(H,22,24)
Inchi Key UEADAWQSJOWXBK-UHFFFAOYSA-N
SMILES C1=CN2C3=C(C=C(C=C3)F)N=C(C2=C1)NNC(=O)C4=NC=CN=C4
Size 5mg
Supplier Page http://www.selleckchem.com/products/sc144.html
Additional Information https://file.selleck.cn/downloads/struct/SC144-chemical-structure-s7124.gif