DMOG
DMOG (Dimethyloxalylglycine) is an antagonist of α-ketoglutarate cofactor and inhibitor for HIF prolylhydroxylase, leading to stabilisation and accumulation of HIF-1α protein in the nucleus. DMOG enhances autophagy.
| Trivial name | Dimethyloxalylglycine |
| Catalog Number | S7483 |
| Molecular Formula | C6H9NO5 |
| CAS# | 89464-63-1 |
| Inchi | InChI=1S/C6H9NO5/c1-11-4(8)3-7-5(9)6(10)12-2/h3H2,1-2H3,(H,7,9) |
| Inchi Key | BNJOZDZCRHCODO-UHFFFAOYSA-N |
| SMILES | COC(=O)CNC(=O)C(=O)OC |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/dmog.html |
| Additional Information | https://file.selleck.cn/downloads/struct/dimethyloxalylglycine-dmog-chemical-structure-s7483.gif |