Nutlin-3
Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells.
| Trivial name | N/A |
| Catalog Number | S1061 |
| Molecular Formula | C7H12O4 |
| CAS# | 890090-75-2 |
| Inchi | InChI=1S/C7H12O4/c1-3-10-6(8)5-7(9)11-4-2/h3-5H2,1-2H3 |
| Inchi Key | IYXGSMUGOJNHAZ-UHFFFAOYSA-N |
| SMILES | CCOC(=O)CC(=O)OCC |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Nutlin-3.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Nutlin-3-chemical-structure-S1061.gif |