Nutlin-3
Nutlin-3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells.
| Trivial name | N/A |
| Catalog Number | S1061 |
| Molecular Formula | C7H13NO3S |
| CAS# | 890090-75-2 |
| Inchi | InChI=1S/C7H13NO3S/c1-5(9)8-6(7(10)11)3-4-12-2/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)/t6-/m0/s1 |
| Inchi Key | XUYPXLNMDZIRQH-LURJTMIESA-N |
| SMILES | CC(=O)NC(CCSC)C(=O)O |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/Nutlin-3.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Nutlin-3-chemical-structure-S1061.gif |