(-)-Xestospongin C
(-)-Xestospongin C is a potent and reversible inhibitor of IP3 receptor that reguates calcium release. (-)-Xestospongin C has been found to inhibit bradykinin-induced Ca2+ release in PC12 cells and attenuate PHP-induced IL-2 production in Jurkat T cells, but exhibits no effect on ryanodine receptor-mediated Ca2+ release in PC12 cells.
| Catalog Number | 88903-69-9 |
| Alternative Name(s) | (1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b']dipyridine; Xestospongin C |
| Molecular Formula | C28H50N2O2 |
| CAS# | 88903-69-9 |
| Inchi | InChI=1S/C28H50N2O2/c1-3-7-15-25-17-21-30-20-10-14-24(28(30)31-25)12-6-2-4-8-16-26-18-22-29-19-9-13-23(11-5-1)27(29)32-26/h23-28H,1-22H2/t23-,24-,25-,26-,27-,28+/m0/s1 |
| Inchi Key | PQYOPBRFUUEHRC-FRZROCRGSA-N |
| Size | Please inquire |
| Supplier Page | https://www.bocsci.com/xestospongin-c-cas-88903-69-9-item-381708.html |