Bafilomycin A1 (Baf-A1)
Bafilomycin A1(Baf-A1) is a vacuolar H+-ATPase inhibitor with IC50 of 0.44 nM. Bafilomycin A1 is found to inhibit autophagy while induces apoptosis.
Trivial name | N/A |
Catalog Number | S1413 |
Molecular Formula | C35H58O9 |
CAS# | 88899-55-2 |
Inchi | InChI=1S/C35H58O9/c1-19(2)32-24(7)27(36)18-35(40,44-32)26(9)31(38)25(8)33-28(41-10)14-12-13-20(3)15-22(5)30(37)23(6)16-21(4)17-29(42-11)34(39)43-33/h12-14,16-17,19,22-28,30-33,36-38,40H,15,18H2,1-11H3 /b14-12-,20-13+,21-16+,29-17-/t22-,23+,24-,25-,26-,27+,28-,30-,31+,32+,33?,35+/m0/s1 |
Inchi Key | XDHNQDDQEHDUTM-MKFMMVOISA-N |
SMILES | CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)O)O)O)OC)C |
Size | 160.6μL(1mM/0.1mg) |
Supplier Page | http://www.selleckchem.com/products/BafilomycinA1.html |
Additional Information | https://file.selleck.cn/downloads/struct/Bafilomycin-A1-chemical-structure-S1413.gif |