Ganetespib (STA-9090)
Ganetespib (STA-9090) is an HSP90 inhibitor with IC50 of 4 nM in OSA 8 cells, induces apoptosis of OSA cells while normal osteoblasts are not affected; active metabolite of STA-1474. Phase 3.
Trivial name | N/A |
Catalog Number | S1159 |
Molecular Formula | C20H20N4O3 |
CAS# | 888216-25-9 |
Inchi | InChI=1S/C20H20N4O3/c1-11(2)14-9-15(18(26)10-17(14)25)19-21-22-20(27)24(19)13-4-5-16-12(8-13)6-7-23(16)3/h4-11,25-26H,1-3H3,(H,22,27) |
Inchi Key | RVAQIUULWULRNW-UHFFFAOYSA-N |
SMILES | CC(C)C1=C(C=C(C(=C1)C2=NNC(=O)N2C3=CC4=C(C=C3)N(C=C4)C)O)O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/ganetespib-sta-9090.html |
Additional Information | https://file.selleck.cn/downloads/struct/Ganetespib-STA-9090-chemical-structure-s1159.gif |