Ripasudil hydrochloride dihydrate
Ripasudil hydrochloride dihydrate is a potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension.
Trivial name | K-115 hydrochloride dihydrate |
Catalog Number | S7995 |
Molecular Formula | C15H18FN3O2S.Cl H.2 H2 O |
CAS# | 887375-67-9 |
Inchi | InChI=1S/C15H18FN3O2S.ClH.2H2O/c1-11-8-17-6-3-7-19(11)22(20,21)14-5-2-4-12-9-18-10-13(16)15(12)14;;;/h2,4-5,9-11,17H,3,6-8H2,1H3;1H;2*1H2/t11-;;;/m0.../s1 |
Inchi Key | CMDJNMACGABCKQ-XVSRHIFFSA-N |
SMILES | CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)F.O.O.Cl |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/ripasudil-k-115.html |
Additional Information | https://file.selleck.cn/downloads/struct/ripasudil-k-115-chemical-structure-s7995.gif |