KU 0060648 50mg
KU0060648 is a potent and selective inhibitor of DNA-dependent protein kinase (DNA-PK), (IC50 = 8.6 nM); with 20-1000 fold selectivity for DNA-PK over other PIKKs and a panel of 60 kinases. KU-0060648 enhances HDR efficiency and attenuates NHEJ frequency.
Trivial name | KU 0060648 50mg |
Catalog Number | A13224-50 |
Alternative Name(s) | 2-(4-Ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo-4H-chromen-8-yl)dibenzo[b,d]thiophen-1-yl)acetamide trihydrochloride |
Molecular Formula | C33H34N4O4S.3HCl |
CAS# | 881375-00-4 |
SMILES | CCN1CCN(CC1)CC(=O)NC2=C3C4=CC=CC=C4SC3=C(C=C2)C5=CC=CC6=C5OC(=CC6=O)N7CCOCC7 |
Size | 50mg |
Supplier Page | http://www.adooq.com/ku-0060648.html |