Serdemetan (JNJ-26854165)

Serdemetan (JNJ-26854165) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. Phase 1.

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Trivial name	N/A
Catalog Number	S1172
Molecular Formula	C14H11ClN2O4
CAS#	881202-45-5
Inchi	InChI=1S/C14H11ClN2O4/c15-10-3-1-2-8(4-10)9-5-11(18)13(16-6-9)14(21)17-7-12(19)20/h1-6,18H,7H2,(H,17,21)(H,19,20)
Inchi Key	JGRXMPYUTJLTKT-UHFFFAOYSA-N
SMILES	C1=CC(=CC(=C1)Cl)C2=CC(=C(N=C2)C(=O)NCC(=O)O)O
Size	25mg
Supplier Page	http://www.selleckchem.com/products/JNJ-26854165.html
Additional Information	https://file.selleck.cn/downloads/struct/JNJ-26854165-chemical-structure-S1172.gif