Aurora Kinase Inhibitor III

Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase with an IC50 of 42 nM and has high selectivity for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively).

Trivial name N/A
Catalog Number S2931
Molecular Formula C21H18F3N5O
CAS# 879127-16-9
Inchi InChI=1S/C21H18F3N5O/c22-21(23,24)14-3-1-4-15(11-14)26-18-9-10-25-20(29-18)28-17-6-2-5-16(12-17)27-19(30)13-7-8-13/h1-6,9-13H,7-8H2,(H,27,30)(H2,25,26,28,29)
Inchi Key RDTDWGQDFJPTPD-UHFFFAOYSA-N
SMILES C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=CC(=N3)NC4=CC=CC(=C4)C(F)(F)F
Size 2mg
Supplier Page http://www.selleckchem.com/products/aurora-kinase-inhibitor-iii.html
Additional Information https://file.selleck.cn/downloads/struct/aurora-kinase-inhibitor-chemical-structure-s2931.gif