Aurora Kinase Inhibitor III
Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase with an IC50 of 42 nM and has high selectivity for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively).
| Trivial name | N/A |
| Catalog Number | S2931 |
| Molecular Formula | C25H29N3O3 |
| CAS# | 879127-16-9 |
| Inchi | InChI=1S/C25H29N3O3/c1-18-22(10-7-11-23(18)20-8-5-4-6-9-20)17-31-24-13-12-21(25(28-24)30-3)16-26-14-15-27-19(2)29/h4-13,26H,14-17H2,1-3H3,(H,27,29) |
| Inchi Key | JEDPSOYOYVELLZ-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC=C1C2=CC=CC=C2)COC3=NC(=C(C=C3)CNCCNC(=O)C)OC |
| Size | 2mg |
| Supplier Page | http://www.selleckchem.com/products/aurora-kinase-inhibitor-iii.html |
| Additional Information | https://file.selleck.cn/downloads/struct/aurora-kinase-inhibitor-chemical-structure-s2931.gif |