EGFR Inhibitor
EGFR inhibitor, a cell permeable, 4,6-disubstituted pyrimidine compound, is a highly selevtive inhibitor of EGFR kinase with IC50 of 21 nM. EGFR inhibitor directly depolymerizes microtubules and is used as a chemical probe to investigate both the EGFR pathway and microtubule dynamics.
Trivial name | EGFR-IN-12 |
Catalog Number | S0360 |
Molecular Formula | C21H18F3N5O |
CAS# | 879127-07-8 |
SMILES | C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=NC(=C3)NC4=CC=CC(=C4)C(F)(F)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/egfr-inhibitor.html |
Additional Information | https://file.selleck.cn/downloads/struct/S0360-EGFR-Inhibitor-chemical-structure-.gif |