Vismodegib (GDC-0449)
Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.
Trivial name | GDC-0449 |
Catalog Number | S1082 |
Molecular Formula | C8H15NO6 |
CAS# | 879085-55-9 |
Inchi | InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6+,7+,8+/m0/s1 |
Inchi Key | MBLBDJOUHNCFQT-LXGUWJNJSA-N |
SMILES | CC(=O)NC1C(C(C(OC1O)CO)O)O |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/GDC-0449.html |
Additional Information | https://file.selleck.cn/downloads/struct/GDC-0449-chemical-structure-S1082.gif |