Vismodegib (GDC-0449)
Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.
Trivial name | GDC-0449 |
Catalog Number | S1082 |
Molecular Formula | C19H14Cl2N2O3S |
CAS# | 879085-55-9 |
Inchi | InChI=1S/C19H14Cl2N2O3S/c1-27(25,26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H,1H3,(H,23,24) |
Inchi Key | BPQMGSKTAYIVFO-UHFFFAOYSA-N |
SMILES | CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/GDC-0449.html |
Additional Information | https://file.selleck.cn/downloads/struct/GDC-0449-chemical-structure-S1082.gif |