Vismodegib (GDC-0449)

Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.

Price Not Available 10mM/1mL Vismodegib (GDC-0449) Supplier Page

Trivial name	GDC-0449
Catalog Number	S1082
Molecular Formula	C19H14Cl2N2O3S
CAS#	879085-55-9
Inchi	InChI=1S/C19H14Cl2N2O3S/c1-27(25,26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H,1H3,(H,23,24)
Inchi Key	BPQMGSKTAYIVFO-UHFFFAOYSA-N
SMILES	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/GDC-0449.html
Additional Information	https://file.selleck.cn/downloads/struct/GDC-0449-chemical-structure-S1082.gif