LXR-623
LXR-623 is a novel liver X-receptor(LXR) agonist with IC50 values of 179 nM and 24 nM for LXR-α and LXR-β, respectively. It is orally bioavailable and readily passes the blood-brain barrier.
Trivial name | WAY-252623 |
Catalog Number | S8390 |
Molecular Formula | C21H12ClF5N2 |
CAS# | 875787-07-8 |
Inchi | InChI=1S/C21H12ClF5N2/c22-18-10-15(24)9-6-13(18)11-29-20(12-4-7-14(23)8-5-12)16-2-1-3-17(19(16)28-29)21(25,26)27/h1-10H,11H2 |
Inchi Key | KYWWJENKIMRJBI-UHFFFAOYSA-N |
SMILES | C1=CC2=C(N(N=C2C(=C1)C(F)(F)F)CC3=C(C=C(C=C3)F)Cl)C4=CC=C(C=C4)F |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/lxr-623-way-252623.html |
Additional Information | https://file.selleck.cn/downloads/struct/lxr-623-way-252623-chemical-structure-S8390.gif |