Quisinostat (JNJ-26481585) 2HCl

Quisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.

Trivial name N/A
Catalog Number S1096
Molecular Formula C8H8O3
CAS# 875320-31-3
Inchi InChI=1S/C8H8O3/c1-11-7-5-3-2-4-6(7)8(9)10/h2-5H,1H3,(H,9,10)
Inchi Key ILUJQPXNXACGAN-UHFFFAOYSA-N
SMILES COC1=CC=CC=C1C(=O)O
Size 5mg
Supplier Page http://www.selleckchem.com/products/JNJ-26481585.html
Additional Information https://file.selleck.cn/downloads/struct/s1096-jnj26481585-chemical-structure-s1096.gif