JUN-1111 | MedChemExpress (MCE)

JUN-1111 is an irreversible and selective Cdc25 phosphatase inhibitor with IC50 values of 0.38, 1.8, 0.66, 28, 37 µM for Cdc25A, Cdc25B, Cdc25C, VHR, PTP1B, respectively. JUN-1111 induces cell cycle arrest at G1 and G2/M phases. JUN-1111 decreases the expression of phosphoCdk1[1][2].

Trivial name JUN-1111
Catalog Number HY-118529
Research Area Cancer
CAS# 874351-38-9
Purity 98.57%
SMILES O=C(C=C1NCCN2CCOCC2)C3=C(N=CC=C3)C1=O
PubChem Chemical Structure ID 11392050
Size 25 mg
Supplier Page https://www.medchemexpress.com/jun-1111.html