IKK-16
IKK-16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM in cell-free assays, respectively. IKK-16 also inhibits LRRK2 Ser935 phosphorylation in cells and LRRK2 kinase activity in vitro with IC50 of 50 nM.
| Trivial name | IKK Inhibitor VII |
| Catalog Number | S2882 |
| Molecular Formula | C8H6N2S3 |
| CAS# | 873225-46-8 |
| Inchi | InChI=1S/C8H6N2S3/c1-5-7(12-13-8(5)11)6-4-9-2-3-10-6/h2-4H,1H3 |
| Inchi Key | CKNAQFVBEHDJQV-UHFFFAOYSA-N |
| SMILES | CC1=C(SSC1=S)C2=NC=CN=C2 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/ikk-16.html |
| Additional Information | https://file.selleck.cn/downloads/struct/IKK-16-chemical-structure-s2882.jpg |