Ivacaftor (VX-770)

Ivacaftor (VX-770) is a selective potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM in fisher rat thyroid cells, respectively.

Price Not Available 10mM/1mL Ivacaftor (VX-770) Supplier Page

Trivial name	VX-770
Catalog Number	S1144
Molecular Formula	C32H38ClN3O2
CAS#	873054-44-5
Inchi	InChI=1S/C32H38ClN3O2/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29/h10-21,24H,4-9,22-23H2,1-3H3
Inchi Key	KJNNWYBAOPXVJY-UHFFFAOYSA-N
SMILES	CCCCC1=NC(=CN1C2=CC=C(C=C2)OC3=CC=C(C=C3)Cl)C4=CC=C(C=C4)OCCCN(CC)CC
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/VX-770.html
Additional Information	https://file.selleck.cn/downloads/struct/VX-770-chemical-structure-S1144.gif