Ro-3306
RO-3306 is an ATP-competitive, and selective CDK1 inhibitor with Ki of 20 nM, >15-fold selectivity against a diverse panel of human kinases. RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis.
| Trivial name | N/A |
| Catalog Number | S7747 |
| Molecular Formula | C18H13N3OS2 |
| CAS# | 872573-93-8 |
| Inchi | InChI=1S/C18H13N3OS2/c22-17-16(24-18(21-17)20-11-14-4-2-8-23-14)10-12-5-6-15-13(9-12)3-1-7-19-15/h1-10H,11H2,(H,20,21,22)/b16-10- |
| Inchi Key | XOLMRFUGOINFDQ-YBEGLDIGSA-N |
| SMILES | C1=CC2=C(C=CC(=C2)C=C3C(=O)NC(=NCC4=CC=CS4)S3)N=C1 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/ro-3306.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ro-3306-chemical-structure-s7747.gif |