Infigratinib (BGJ398)

Infigratinib (BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM in cell-free assays, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2.

Price Not Available 5mg Infigratinib (BGJ398) Supplier Page
Trivial name NVP-BGJ398
Catalog Number S2183
Molecular Formula C26H31Cl2N7O3
CAS# 872511-34-7
Inchi InChI=1S/C26H31Cl2N7O3/c1-5-34-10-12-35(13-11-34)18-8-6-17(7-9-18)31-21-15-22(30-16-29-21)33(2)26(36)32-25-23(27)19(37-3)14-20(38-4)24(25)28/h6-9,14-16H,5,10-13H2,1-4H3,(H,32,36)(H,29,30,31)
Inchi Key QADPYRIHXKWUSV-UHFFFAOYSA-N
SMILES CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl
Size 5mg
Supplier Page http://www.selleckchem.com/products/bgj398-nvp-bgj398.html
Additional Information https://file.selleck.cn/downloads/struct/BGJ398-chemical-structure-s2183.gif