H-1152 dihydrochloride
H-1152 dihydrochloride (2HCl) is a membrane-permeable and selective inhibitor of Rho-associated protein kinase (ROCK). H-1152 inhibits ROCK2, PKA, PKC, PKG, AuroraA and CaMK2 with IC50 of 0.0120 μM, 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
Trivial name | H-1152 2HCl |
Catalog Number | S6214 |
Molecular Formula | C16H23Cl2N3O2S |
CAS# | 871543-07-6 |
Inchi | #N/A |
Inchi Key | #N/A |
SMILES | Cl.Cl.CC1CNCCCN1[S](=O)(=O)C2=CC=CC3=C2C(=CN=C3)C |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/h-1152-dihydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/s6214-h-1152-dihydrochloride-chemical-structure.gif |