GW2580
GW2580 (SC-203877) is a selective CSF-1R inhibitor for c-FMS with IC50 of 30 nM, 150- to 500-fold selective compared to b-Raf, CDK4, c-KIT, c-SRC, EGFR, ERBB2/4, ERK2, FLT-3, GSK3, ITK, JAK2 etc.
| Trivial name | SC-203877 |
| Catalog Number | S8042 |
| Molecular Formula | C20H22N4O3 |
| CAS# | 870483-87-7 |
| Inchi | InChI=1S/C20H22N4O3/c1-25-16-6-3-13(4-7-16)12-27-17-8-5-14(10-18(17)26-2)9-15-11-23-20(22)24-19(15)21/h3-8,10-11H,9,12H2,1-2H3,(H4,21,22,23,24) |
| Inchi Key | MYQAUKPBNJWPIE-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(C=C1)COC2=C(C=C(C=C2)CC3=CN=C(N=C3N)N)OC |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/gw2580.html |
| Additional Information | https://file.selleck.cn/downloads/struct/GW2580-chemical-structure-s8042.gif |