acalisib (GS-9820)
Acalisib (GS-9820, CAL-120) is a highly selective and potent p110δ inhibitor (IC50 = 14 nM) with 114- to 400-fold selectivity over the other class I PI3K enzymes and no activity against Class II and III PI3K family members or other PI3K-related proteins including mTOR and DNA-PK.
| Trivial name | CAL-120 |
| Catalog Number | S5818 |
| Molecular Formula | C41H62N12O11 |
| CAS# | 870281-34-8 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | CCC(C)C(NC(=O)C(CC1=CC=C(O)C=C1)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(CC2=CN=C[NH]2)C(=O)N3CCCC3C(O)=O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/acalisib-gs-9820.html |
| Additional Information | https://file.selleck.cn/downloads/struct/acalisib-gs-9820-chemical-structure-s5818.gif |
