MLN8054
MLN8054 is a potent and selective inhibitor of Aurora A with IC50 of 4 nM in Sf9 insect cell. It is more than 40-fold selective for Aurora A than Aurora B. Phase 1.
| Trivial name | N/A |
| Catalog Number | S1100 |
| Molecular Formula | C25H15ClF2N4O2 |
| CAS# | 869363-13-3 |
| Inchi | InChI=1S/C25H15ClF2N4O2/c26-15-6-9-17-18(10-15)23(21-19(27)2-1-3-20(21)28)29-11-14-12-30-25(32-22(14)17)31-16-7-4-13(5-8-16)24(33)34/h1-10,12H,11H2,(H,33,34)(H,30,31,32) |
| Inchi Key | HHFBDROWDBDFBR-UHFFFAOYSA-N |
| SMILES | C1C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)C(=N1)C4=C(C=CC=C4F)F)NC5=CC=C(C=C5)C(=O)O |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/MLN8054.html |
| Additional Information | https://file.selleck.cn/downloads/struct/MLN8054-chemical-structure-S1100.gif |