Pyrimorph is a fungicide with excellent antifungal activity against oomycetes.In Vitro: Pyrimorph inhibits different stages in the life cycle of P.capsici: mycelial growth (EC50 = 1.84 μg/mL), sporangia formation (EC50 = 0.17 μg/mL), zoospore release (EC50 = 4.92 μg/mL), cystospore germination (EC50 = 0.09 μg/mL).
Pyrimorph exhibits 40.95% inhibition of oxygen consumption of intact mycelia at 100 μg/mL.
Pyrimorph inhibits the synthesis of cell wall either directly or indirectly from ultrastructural transformation of cell wall thickening and disruption of vacuoles.In Vivo: Pyrimorph (0-28 mg/L; exposure; 0-192 h) has low toxicity and accumulates quickly in zebrafish[2].