Linsitinib (OSI-906)

Linsitinib (OSI-906) is a selective inhibitor of IGF-1R with IC50 of 35 nM in cell-free assays; modestly potent to InsR with IC50 of 75 nM, and no activity towards Abl, ALK, BTK, EGFR, FGFR1/2, PKA etc. Phase 3.

Price Not Available 10mM/1mL Linsitinib (OSI-906) Supplier Page

Trivial name	N/A
Catalog Number	S1091
Molecular Formula	C26H23N5O
CAS#	867160-71-2
Inchi	InChI=1S/C26H23N5O/c1-26(32)14-19(15-26)25-30-22(23-24(27)28-11-12-31(23)25)18-8-7-17-9-10-20(29-21(17)13-18)16-5-3-2-4-6-16/h2-13,19,32H,14-15H2,1H3,(H2,27,28)/t19-,26+
Inchi Key	PKCDDUHJAFVJJB-VLZXCDOPSA-N
SMILES	CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/OSI-906.html
Additional Information	https://file.selleck.cn/downloads/struct/OSI-906-chemical-structure-s1091.gif