(R)-(-)-Gossypol acetic acid

AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID. Phase 2.

Catalog Number T6396
Alternative Name(s) AT101醋酸 , (-)-Gossypol acetic acid , AT101 , AT-101 (acetic acid) , AT101 acetate , (R)-Gossypol acetic acid
Research Area Autophagy|||Apoptosis
Molecular Formula C30H30O8·C2H4O2
CAS# 866541-93-7
Purity 96.73%
SMILES CC(O)=O.CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O
Size 5 mg
Supplier Page https://www.targetmol.com/compound/(R)-(-)-Gossypol acetic acid
Additional Information https://www.targetmol.com/datasheet/T6396