SN-38
SN-38 (NK012) is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. SN-38 induces autophagy.
| Trivial name | NK012 |
| Catalog Number | S4908 |
| Molecular Formula | C22H20N2O5 |
| CAS# | 86639-52-3 |
| Inchi | InChI=1S/C22H20N2O5/c1-3-12-13-7-11(25)5-6-17(13)23-19-14(12)9-24-18(19)8-16-15(20(24)26)10-29-21(27)22(16,28)4-2/h5-8,25,28H,3-4,9-10H2,1-2H3/t22-/m0/s1 |
| Inchi Key | FJHBVJOVLFPMQE-QFIPXVFZSA-N |
| SMILES | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)O |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/sn-38.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SN-38-chemical-structure-s4908.gif |